Therapeutic Actions
1. Chronic Pain Relief: peripheral neuropathy, arthritis, back pain, carpal tunnel,
tendon problems.
2. Improves healing response at the site of injuries.
3. Imrovement of energy, focus, mental function and relaxation.
4. Promotes cerebral functioning.
5. Supports cellular longevity.
6. Anti-inflammatory and antioxidant effects.
7. Increases the function of haemapoietic stem cell actions.

Formula Rationale
StemCell is a proprietary herbal formula designed to improve the functioning of the body’s own (endogenous) stem cells. Current case studies with chronic pain patients indicate that his formula
may help to initiate cellular repair, improve mood and reduce pain in patients with osteoarthritis, low back pain, carpal tunnel syndrome, and peripheral neuropathy.

A 12-patient double-blind crossover study supports past in vivo animal and in vitro cells studies of a unique novel nutraceutical combination of vitamin D3, blueberry fruit extract, green tea leaf
extract and carnosine to enhance blood stem cell activity.

The 12-patient study shows that natural substances in a synergistic combination can increase blood stem cell activity, promote healing of injury, decrease cellular senescence and support general
health and wellbeing. Along with the measured physiological effects, study participants reported that StemCell improved their energy, focus, stress, mental function and relaxation using standard
questionnaires.

Royal Jelly is a concentrated bee product, which has been used in traditional medicine. Yamada Royal Jelly has been the subject of clinical and experimental studies in the areas of immune
performance, inflammation, kidney toxicity, muscle strength, low back pain, anxiety, and bone strength osteoporosis. Yamada Royal Jelly is enzyme treated to remove allergic
components.

Various in vitro experiments have examined the actions of royal jelly and its constituents on the immune system demonstrating positive effects on bone marrow stem cells. Vitamin D3 is an essential nutrient involved with bone health and immunity. Active vitamin D is sent to different areas of the body including bones intestines, colon, brain and immune cells, all of which have Vitamin D receptors.

Recent research on the use of Spirulina (arthrospira platensis) shows that it triggers the mobilization of stem cells. A diet supplemented with spirulina was able to negate the LPS induced decrease
in stem/progenitor cell proliferation. Spirulina can act as an anti-inflammatory, and reverse the age-related elevation of TNF-α.

Blueberry supplementation useful as a stimulator of reparative processes associated with mobilization of hematopoietic and endothelial progenitors. Dietary supplementation with 2% blueberry
extract has produced both neuroprotective and neurorestorative effects in aged animals, perhaps as a result of modulation of cell signaling cascades. Furthermore, blueberry extract has been shown
to increase neurogenesis in laboratory experiments. Blueberry may reverse cellular and behavioral parameters that decline as a function of aging.

Carnosine is a naturally occurring dipeptide present at high concentration in a range of human tissues. Carnosine is an amino acid with strong antioxidant properties. It is highly concentrated
in skeletal muscle and brain tissues. It is often referred to as the anti-aging and antioxidant dipeptide.

Recent studies suggest that epigallocatechin‐3‐gallate (EGCG), which is the main polyphenolic constituent of green tea, may be used for the prevention and treatment of various neurodegenerative
diseases.

Fucoidans have been the subject of preliminary studies to investigate claims for potential antioxidant, cognitive, anti-inflammatory, anti-angiogenic, anti-cancer, anti-viral, and anti-hyperglycemic effects.

In conclusion, StemCell helps patients in chronic pain through a variety of mechanisms including tissue injury repair. In may be a benefit to other patients with chronic disease associated with aging. Many patients using the formula have reported improved mood and energy levels.

• Vitamin D3 (as Cholecaliferol) 200mcg.
• Spirulina algae (Arthrospira spp.) 600mg.
• Blueberry fruit extract 5:1 (Vaccinum spp.) 500mg.
• Royal Jelly (enzyme treated) 333mg.
• Fucoidan 200mg.
• Green Tea leaf extract (Camellia sinensis) 100mg.
• L-Carnosine 50mg.